How Much Does The Process Of Synthesizing A Gene Cost? 

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Have you ever heard of Gene Synthesizing before? Gene synthesis creates a gene in vitro without the need for an initial template. Contrary to popular assumptions, commercial gene synthesis services rapidly grow to become a cost-effective alternative to classical cloning and other molecular biological processes.  

Uncoating the genome is triggered by early gene synthesis, followed by genome replication, which requires intermediate gene synthesis, late gene synthesis, and virion morphogenesis. Eurofins Genomics has the best gene synthesis, division. The following are underlying costs associated with the process of synthesizing a gene as discussed below; 

Custom gene synthesis 

Custom gene synthesis services consider all the molecular biology needs without compromising quality. Gene synthesis cost per base pair has reduced from around 10 dollars per base pair to around 0.10 dollars per base pair in the last ten years, similar to the dramatic decrease in sequencing a human genome. Increased technology and many companies providing this technology have driven down the cost of gene synthesis. Synbio technologies take pride in being one of the leading gene synthesis firms, offering some of the lowest prices in the industry while producing high-quality results.

While the cost of gene synthesis has decreased, the quality of the product has deteriorated. Quality and possible gene lengths have both improved as costs have decreased. Synbio Technologies can accurately synthesize genes up to 150 kilobytes in length. Aside from its quality, gene synthesis applications have expanded dramatically, resulting in a surge in popularity. 

Gene synthesis is a prominent scientific tool for developing more effective vaccines and GMOs. The link is reduced gene synthesis costs, expanded applications, and improved quality. Gene synthesis is a powerful tool many researchers employ in their research workflows. It is a tried-and-true technology that revolutionized genetic research. When these benefits combine with the inexpensive cost of gene synthesis, it’s easy to understand why this process is so popular among geneticists.

Synbio Technologies offer some of the lowest prices per base pair because of the decrease in gene synthesis while still delivering high-quality results. It also can give the highest-quality sequence at the lowest cost to customers.  

Gene synthesis is a dependable and cost-effective technology for creating bespoke DNA constructs with perfect sequence precision. DNA synthesis is becoming a critical aspect of the research workflow and has altered modern biology as a strong molecular tool. It leads to high levels of recombinant protein expression when combined with effective gene design techniques that optimize codon usage. 

GenScripts DNA synthesis process 

To ensure 100 percent sequence correctness, GenScripts’ DNA synthesis process uses on-site sequence optimization and oligo design, followed by oligo synthesis and gene assembly. Creating vast pools of genes has long been a source of frustration for biotechnologists, but now US researchers can construct collections of thousands of different DNA strands for a fraction of the cost.  

The University of California, Los Angeles, named their method DropSynth, which costs less than 2 dollars [1.48 Euros] per gene. For the shortest genuine genes the team has developed, existing commercial providers price at least 25 dollars. One person may generate ten thousand genes which cost 1 million dollars and require a consortium.   

Moore’s Law 

Moore’s law has been demonstrated and utilized in various fields, including biotechnology and technology. Moore’s law was demonstrated in genetics when the cost of sequencing the human genome was calculated. The first human whole-genome sequencing was performed in the early two-thousands, costing around a hundred million dollars.

The technology for sequencing the human genome has rapidly advanced in the last ten to fifteen years, dramatically lowering the cost of sequencing. An entire human genome sequence now costs under a thousand dollars, less than 1 percent of what it cost ten to fifteen years ago. Moore’s law had a variant in this rapid cost drop. 

Regardless of the price per base pair, there’s usually the lowest price for each gene. For example, at 0.09 dollars per bp, a 500- bp gene will cost 45 dollars. However, because the minimum price per gene is 99 dollars, that gene’s price will be equal to 99 dollars instead. 

Gene synthesis [together with the discipline it has enabled, synthetic biology] has prompted a lot of conjecture and start-up activity, as it does with many other new technologies in their early stages. 

The majority of the companies are still in the experimental stages, with no convincing results yet. Whether creating microbes to make industrial chemicals or designing human cells to cure medical problems, the possibilities fascinate both investors and scientists. If even a fraction of these attempts succeed, trillion-dollar marketplaces may emerge. 


We have discussed how much processing a gene synthesizing costs. We’ve also learned a lot about the importance of gene synthesis. It enables the creation and modification of genetic sequences at an unprecedented pace, offering enormous potential for new biological functionality. This data shows us the cost of gene synthesizing, and it’s also important within a laboratory setting for biologists. 

By Michael Caine

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